Objective: To determine the efficacy of intralesional triamcinolone acetonide in alopecia areata by Dermojet.
Methodology: This study was a case series and conducted in Dermatology department, Abbasi Shaheed Hospital, Karachi, Pakistan from February 6, 2014 to August 6, 2014. Clinically diagnosed, 100 cases of alopecia areata aged 15 to 50 years were included via non probability consecutive sampling. Intralesional triamcinolone acetonide was given via Dermojet at monthly intervals for 3 months. The response was recorded at each visit by the appearance of hairs in alopecia patches. The efficacy was taken as positive if more than 50% of the patch showed growth of hairs with reduction in size of the patch, as measured by Vernier Caliper.
Results: The mean age was 30.84±9.97 years (range 15 to 50). Out of 100 patients, 44 were male and 56 female. Only 19 patients had a positive family history. The mean duration of disease was 6.88±4.90 months. 86 patients had 1-3 patches and 14 patients had 4-6 patches while mean size of the patch was 4.33±1.72 cm. 75 patients achieved efficacy and 25 patients did not.
Conclusion: The efficacy of intralesional triamcinolone acetonide in alopecia areata patches via Dermojet device was high. It may be utilized in future for treatment of alopecia areata.
Key words: Alopecia areata, triamcinolone acetonide, intralesional, Dermojet, efficacy.
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