Background: Glomus tumors are benign and rare vascular tumors, with an incidence of less than 2% in relation to all soft tissue tumors. About 75% occur in hand, especially in the nail bed, even though these tumors may also occur in atypical locations. They are characterized by a triad composed of pain, cold intolerance, and point tenderness.
Case Presentation: We present a clinical case of a male patient with 67 years old with a painful lesion on the subcutaneous tissue of the knee with 5 years of evolution. The pain exacerbated with the cold. He underwent surgical excision with pain resolution, and no recurrence or metastasis was found at 30-month follow-up.
Conclusion: The rapid diagnosis of glomus tumors is important to avoid treatment delays leading to chronic pain. It is important to consider glomus tumors in the differential diagnosis of subcutaneous lesions.
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