Aim: Chlorhexidine (CHX) and benzydamine hydrochloride (B-HCl) combination treatment (Kloroben spray) was compared with sodium pentaborate pentahydrate (NaB, also called boron) treatment with regard to their effects in the recovery of recurrent aphthous stomatitis (RAS).
Materials and Methods: We assessed the treatment results by evaluating ulcer radius and VAS results. Seventy-one patients with clinically diagnosed minor RAS were selected for the study based on inclusion and exclusion criteria. Group 1 was treated with a 3% solution of NaB and group 2 was treated with Kloroben spray (45 mg benzydamine HCl and 36 mg chlorhexidine gluconate) for 1 week.
Results: After the treatments, there were statistically significant decreases in VAS scores in both Group 1 (p
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