Most of the bioactive molecules are synthesised by time-consuming conventional methods. The use of toxic chemicals harms the environment and human beings. In this review, an attempt has been made to introduce methods and procedures related to the green and environment benign synthetic process. Until 1980s the knowledge of the risks associated with using chemicals was quite poor among the chemists. This review mainly focuses on the green synthesis of Indazoles, Benzimidazoles, Coumarins, Pyrazoles and Imidazoles. As on today, toxicity of the chemicals can be explained to eliminate the cause of its toxicity without sacrificing the desirable properties of the chemical.
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