Objective: In this study, we aimed to evaluate the relationship between neutrophil lymphocyte ratio (NLR), CRP and disease severity in 0-2 years old children diagnosed and hospitalized with bronchiolitis.
Material and Methods: In this prospective cross-sectional study, 158 patients aged 0-2 years who were hospitalized for bronchiolitis between the dates 01.12.2018 and 04.01.2020 in Health Sciences University Bağcılar Training and Research Hospitals Pediatrics clinic were included. Patients' age, gender, laboratory results and disease severity scoring were recorded. According to this, disease severity was evaluated as mild, moderate and severe.
Results: No statistically significant difference was observed between the disease severity score and the mean age of the groups, and the gender distribution (p=0.061, p=0.392). A statistically significant difference was found between the disease severity score and the neurotrophil/lymphocyte (N/L) ratios (p=0.007). The N/L ratio of the mild group was found to be statistically significantly lower than moderate and severe groups (p=0.003, p=0.006). No statistically significant correlation was observed between the disease severity score and mean age of the moderate and severe groups (r=0.081 p=0.311) . A statistically significant difference was observed between the disease severity score and CRP values (p=0.014). The CRP values of the group with mild disease were found to be significantly lower than the group with moderate severity (p=0.04).
Conclusion: An increase in the neutrophil-lymphocyte ratio, along with CRP, is associated with the clinical severity and is a beneficial parameter that can be used to evaluate the prognosis of 0-2 years old hospitalized patients with bronchiolitis.
Key words: Keywords: bronchiolitis, neutrophil lymphocyte ratio, disease severity, CRP
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