Background: Smoking of cigarettes has been found to alter lipoprotein levels. Smoking raises the blood total cholesterol (TC) content, triglycerides (TG), low-density lipoprotein (LDL), and very LDL (VLDL) and reduces the level of good cholesterol, i.e., high-density lipoprotein (HDL).
Aim and Objective: The aim of this study was to find out the association between lipid profile and smoking among the patients.
Materials and Methods: A hospital-based cross-sectional study at Outpatient Department, Gandhi Medical College, Hyderabad, for 6 months from January 2019 to July 2019. The study was performed among 100 people who were being treated with various illnesses at the hospital. There were 50 non-smokers and 50 smokers in this study. Based on smoking frequency, the smokers were further split in three classes. Serum lipid profile was evaluated in all the patients.
Results: The mean TC was found to be 160.29 ± 27.89 in the non-smokers compared to 192.96 ± 32.37 in the smokers. The mean TG in non-smokers was found to be comparatively lesser at 105.61 ± 25.82 than smoker group with 165.29 ± 28.95. The mean HDL was found to be less in smokers at 44.62 ± 9.98 compared to non-smokers, where the mean was 48.91 ± 8.70. The mean LDL was comparatively lower in non-smokers with a mean of 81.20 ± 15.93 when compared to smokers with a mean of 104.09 ± 19.54. The VLDL was lower in the non-smokers with a mean of 20.96 ± 6.52 when compared to smokers 29.23 ± 9.20.
Conclusions: A strong correlation between smoking and increased serum lipids is clearly established in this research. The risk of increasing serum cholesterol in heavy smokers by raising LDL cholesterol and decreasing the amount of HDL cholesterol is significant because this effect is correlated with a coronary heart disease.
Key words: Cigarette Smoking; Triglycerides; Low-density Lipoprotein; Very High-density Lipoprotein; High-density Lipoprotein; Cholesterol
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