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Original Research

BMB. 2021; 6(4): 0-0


BhCG as a rupture marker in ectopic pregnancy:a retrospective study

Özlem Karabay Akgül, Evrim Ebru Kovalak, Toygun Çakmak, Hakan Güraslan.




Abstract

BhCG as a rupture marker in ectopic pregnancy:a retrospective study
Objective: To find effective criteria in determining the risk of ectopic pregnancy rupture in patients with ectopic pregnancy.
Material and method: The data of 101 patients who were hospitalized with the diagnosis of ectopic pregnancy in the tertiary center between January 2018 and January 2021 were analyzed retrospectively. Demographic data of the patients, the month of admission, the patients’ BhCG value at the time of admission, blood type, endometrial thickness measured with transvaginal ultrasound, presence of adnexal mass suggestive of ectopic pregnancy and treatments applied to the patients were recorded. These data were compared between patients who had surgery for ectopic pregnancy rupture and those whose treatment was completed without it.
Results: In the statistical analysis of the data, ectopic pregnancy rupture was found significantly more frequent for a threshold value of BhCG >4000 IU/L. Other data were not statistically significant.
Conclusion: In cases of ectopic pregnancy, if the BhCG value at the time of admission exceeds the threshold value, the possibility of surgical approach increases. Medical treatment may be more successful at lower BhCG levels.
Ektopik gebelikte bir rüptür belirteci olarak BHcg:retrospektif çalışma
Amaç:Ektopik gebelik saptanmış hastalarda rüptür riskinin belirlenmesinde etkili kriterleri bulmak.
Yöntem ve Gereçler: Ocak 2018- Ocak2021 tarihleri arasında tersiyer merkezde yatarak takibi yapılan 101 ektopik gebelik vakasına ait demografik ve medikal kayıtlar retrospektif olarak değerlendirilmiştir.Hastaların başvurduğu ay,kan grubu, yatış anındaki ilk BHcg değeri,ultrasonografik incelemede endometrial kalınlık ve ektopik gebelik odağının varlığı kaydedilmiştir ve bu veriler ameliyat olması gereken ve gerekmeyen gruplar arasında karşılaştırılmıştır.
Bulgular: İstatistiksel analizde BHcg >4000 IU/L olana hastalarda anlamlı olarak rüptürün daha fazla olduğunu gördük. Diğer veriler istatistiksel olarak anlamlı değildi.
Sonuçlar: Ektopik gebelik vakalarında başvuru anındaki yüksek BHcg değeri cerrahi gerekmesi ihtimalini arttırır. Daha düşük BHcg değerlerinde medikal tedavi daha başarılı sonuç sağlar.

Key words: ectopic pregnancy, tubal rupture, methotrexate, Bhcg threshold






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