Objective: we aimed to investigate the relationship between neonatal and pregnancy outcomes and cervicovaginal smear-determined reactive cellular changes and/or inflammation revealing an infectious agent in the first trimester of pregnant patients.
Method: In a group of 153 pregnant women who are in their first trimester period were enrolled to the study. Records related to the pregnancy and neonates were identified nad further analyzed.
Results: In terms of smear results, among 152 patients, 54 (35.5%) were reported as normal, while 96 (63.2%) with reactive cellular changes and/or inflammation, and 2 (1.3%) with ASCUS (atypical squamous cells of which significance were not determined). In 117 patients (76.4%) no infectious agent was observed, while 22 patients (14.5%) had fungus (candida), 8 had protozoon (trichomonas vaginalis), 5 (3.3%) had bacterial vaginosis (BV). There was no statistically significant difference observed for average pregnancy weeks, baby's birth weight, preterm birth and neonatal intensive care unit internation in between patient who have reactive cellular changes and/or inflammation and normal smear results (P=0.72, P=26, P=0.44, P=0.52).
Conclusion: We found no association between inflammation or reactive cellular changes of smear results in the first trimester of pregnancy and adverse pregnancy or neonatal outcomes as being a first research in our country.
Key words: pregnancy, smear, vaginal infections, preterm birth, neonatal outcome
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