Intrabiliary metastasis of colon cancer without the involvement of the hepatic parenchyma is very rare and can cause biliary obstruction. We herein present a rare case of colon cancer metastasis that developed after right hemicolectomy and while undergoing chemotherapy. Computed tomography (CT) of the abdomen and percutaneous transhepatic cholangiography and drainage (PTCD) was performed because of obstructive jaundice. CT-guided biopsy showed high-grade atypical glands that were CK7(−), CK20(+), and CDX-2(+); metastatic adenocarcinoma would be considered first rather than cholangiocarcinoma. Clinicians should be aware that intrabiliary metastasis of colon cancer can mimic cholangiocarcinoma and chemotherapy-induced sclerosing cholangitis.
Key words: Intrabiliary metastasis, colon cancer, cholangiocarcinoma
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