Angiotensin II receptor blockers (ARBs) are the antihypertensive drugs associated with side effects, majorly like cough and electrolyte disturbance. Azilsartan is a newly marketed ARB in India, not even having well established adverse effects profile. Here we present a 58-year-old female who was admitted to the emergency department showing signs and symptoms of delirium, disorientation and vomiting for four days. The patient is known to have coronary artery disease (CAD) for that she underwent coronary artery bypass grafting (CABG). She was recently started on azilsartan for her chronic hypertension along with other drugs. The presence of electrolyte imbalance in laboratory reports and current symptoms suggested of azilsartan induced encephalopathy. The patient was recovered after discontinuation of azilsartan. This case enlightens the clinical characteristics, possible mechanism and treatment strategy opted to correct the condition.
Key words: Angiotensin II receptor blocker, Hyperkalemia, Hyponatremia, Hypertension, Renin-angiotensin-aldosterone-system
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