Introduction: Pre-eclampsia is a major cause of maternal mortality and morbidity, preterm birth, perinatal death, and intrauterine growth restriction in global maternity cases.
Purpose: The study aims to investigate the role of pro-inflammatory and anti-inflammatory cytokines in the pathophysiology of preeclampsia.
Method: In order to get cross sectional data, The study employed observation method. The serum IL-6 and IL-10 of the subjects with preeclampsia and normal pregnancies were measured. The systolic, diastolic blood pressures, and proteinuria of the subjects were also checked. The results were evaluated using the t-test, the Kruskal-Wallis test, and the Spearman correlation test (P
Key words: Preeclampsia, interleukin-6, interleukin-10, inflammation, pathogenesis
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