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Effects of pericardiotomy on left ventricular muscle mass and hemodynamic parameters

Mehmet Kizilay, Senol Yavuz.




Abstract
Cited by 0 Articles

Aim: It has been shown in many experimental animal studies that increased myocardial tension and ventricular filling after cardiac pericardiectomy leads to increased myocardial protein synthesis and increased left ventricular muscle mass. In this study, we aimed to show left ventricular muscle mass changes, left ventricular end-systolic-end-diastolic volume changes, significant changes in systolic-diastolic blood pressure and wall stress after pericardiectomy performed in patients with normal ejection fraction undergoing coronary artery bypass graft (CABG) operation.
Material and Methods: Echocardiographic ventricular mass, end-diastolic volumes, end-systolic volumes, ejection fraction values were measured in the preoperative 1st day, postoperative 6th weeks and post operative 6th months in our 32 patients with normal ejection fraction who underwent elective coronary artery bypass operation in our clinic.
Results: According to the preoperative values, echocardiographic evaluations showed that left ventricular muscle mass index (LVMMI) increased 15% at 6 weeks, %18 at 6 month after CABG operation ( p< 0,05). The mean left ventricular end diastolic volume index (LVEDVI) was 55 ±8 ml/m2 preoperatively , 67 ±10 ml/m2 at the 6th week and 70 ±12 ml/m2 at 6th month; this increase was significant respectively (p

Key words: Left ventricular muscle mass; CABG; pericardiectomy






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