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Original Research

RMJ. 2021; 46(1): 33-36


Effect of anti-oxidant (α-lipoic acid) treatment on the improvement of diabetic neuropathic pain.

Nasir Siddique, Faisal Awais, Muhammad Shakil, Sadaf Sarwar, Nargis Haider Kakar, Muhammad Ikram Ullah.




Abstract

Objective: To compare the mean change in total symptom score (TSS) or neuropathic symptom score (NSS) in diabetic patients taking α-lipoic acid and in controls taking usual treatments.
Methodology: This randomized control trial study comprised of 110 patients who were divided into equal treatment group and control group. The mean change in TSS was determined in both groups. Data analysis was performed by using SPSS version 20.
Results: Mean age of patients with treatment group was 46.09±11.86 years and in control group 47.67±10.66 years. Male to female ratio was 1.03:1. The mean change in TSS in treatment group was 2.38±1.99 and in control group was 0.53±1.32 (p

Key words: Diabetes mellitus, complication, neuropathy.






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