Objective:, To evaluate tracheal intubation condition in adults after anesthetic coinduction with
lidocaine and propofol and various doses of remifentanil.
Materials and Methods:. In three groups, induction was compared with lidocaine (1.5 mg/kg),
propofol (2 mg/kg), and three varing doses of remifentanil (0.5-1-2 μg/kg). Tracheal intubation
was graded according to the ease of laryngoscopy, the position of vocal cords, coughing, jaw
relaxation and the movement of limbs. Hemodynamic variables were compared during
preoxygination and 45 seconds after induction.
Results: There were 90 ASA I or ASA II patients with 30 in each group. Tracheal intubating
condition was regarded as acceptable in 33%, 53% and 90% of patients in groups 1, 2 and 3
respectively. All three groups had a decrease in heart rate and mean arterial pressure after
induction but this changes wasn’t clinically significant.
Conclusion: Tracheal intubating condition was best after induction with lidocaine 1.5mg/kg,
propofol 2mg/kg and remifentanil 2μg/kg. (Rawal Med J 2006;31:20-24)
Key words: Remifentanil, propofol, tracheal intubation, analgesic opioids.