Malignant peritoneal mesothelioma is a rare entity arising either as a primary malignancy or as part of pleuro-peritoneal manifestation. We report a case of forty-three years old male who was previously treated for malignant pleural mesothelioma and underwent F-18-Fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) for evaluation of weight loss and abdominal discomfort of recent onset. The scan revealed extensive metabolically active mass like thickenings of the peritoneum at multiple sites that turned out to be of mesothelial origin on peritoneal biopsy. No metabolically abnormal findings were revealed in the chest region on the scan. Our case demonstrates the role of FDG PET-CT in detecting sites of malignant mesothelial involvement other than pleura.
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