Aim: There is a need for inexpensive, reliable and readily available biomarkers in the early diagnosis and prediction of mortality, morbidity and treatment response in colorectal cancer (CRC). In our study, it was aimed to compare MPV (mean platelet volume), RDW (red cell distribution width) and NLR (neutrophil-lymphocyte ratio) measurements in operated and non-operated patients with diagnosis of CRC.
Method: In our study, we retrospectively reviewed 52 patients (including 26 operated patients and 26 non-operated patients) diagnosed as CRC with colonoscopic biopsy at endoscopy unit of gastroenterology department between 2016 and 2019. We extracted and compared demographic, colonoscopy, clinical, laboratory and surgical data in both groups.
Results: In our study, mean age (60.04 years and 64.19 years, respectively) and gender distribution (female: male, 12: 14 and 11: 15, respectively) were comparable in operated and non-operated patients with CRC. MPV, RDW and NLR measurements were found to be significantly lower in patients underwent surgery (operated) when compared to non-operated patients (p
Key words: NLR (neutrophil-lymphocyte ratio), MPV (mean platelet volume) and RDW (red cell distribution width), operation, colorectal adenocarcinoma
|
