Psychosis is a well-known presentation of autoimmune encephalitis. We report a case of a young female presenting with psychotic symptoms followed by neuroleptic malignant syndrome secondary to antipsychotics. The primary diagnosis was anti-NMDAR encephalitis which was complicated with reversible splenial lesion syndrome. Following the surgical excision of the teratoma, she made a complete recovery.
Key words: Autoimmune encephalitis, Neuroleptic malignant syndrome, Anti-NMDAR antibodies, Reversible splenial lesion syndrome, Psychosis
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