Abstract

The literature about manic reactions as side effects of antimicrobial agents is restricted to a limited number of case reports. We here present a secondary mania case due to antibiotic use with a positive family history for mood disorders. We report the case of a 16-year-old patient developed an acute manic psychosis after 1 week administration of amoxicillin. Patient was treated with lithium and risperidone. In the first week of the treatment with mood stabilizer and an antipsychotic patient’s Brief Psychiatric Rating Scale and Young Mania Rating Scores decreased and patient was discharged. Antibiotic agents may trigger a mood disorder in individuals with a positive family history and discontinuation of the antibiotic agent may not be enough to alleviate the symptoms. Mood stabilizers and other antimanic agents are frequently needed.

Key words: Bipolar disorder, antibiomani, amoxicillin