Immune checkpoint blockade therapy (ICB) targets immune suppressive checkpoint proteins, such as programmed cell death 1 (PD-1) / programmed cell death ligand 1 (PD-L1) and cytotoxic T-lymphocyte antigen 4 (CTLA 4) pathways. It exhibits a significant advantage in non-small cell lung cancer (NSCLC) treatment. Number of Patients with immune related adverse events (irAEs) are likely to grow due to the large amounts of patients being administered ICB for NSCLC. This report demonstrates a case of aplastic anemia (AA) secondary to ICB therapy in a patient with NSCLC, and a specific treatment for the AA by immune suppression therapy (IS). The study of IS therapy indicates it is an important therapeutic tool for patients with AA; however, it is unclear how IS therapy works for NSCLC patients with a secondary AA under an ICB treatment. This clinical case provides a positive result and indicates IS therapy can be used on AA secondary to ICB therapy. More study is needed to investigate for potential side effects of this treatment.
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
We use cookies and other tracking technologies to work properly, to analyze our website traffic, and to understand where our visitors are coming from. More InfoGot It!
