Abstract

Background: Percutaneous coronary intervention (PCI) has become the treatment method for patients presenting with ST elevation myocardial infarction (STEMI). One of the well-known complications of PCI is no-reflow. Studies demonstrated relationship between endothelial dysfunction and disturbed vascular flow due to angulation of vascular tree. Although relationship between hemodynamic alterations and coronary angulation is evident, there is a lack of detailed analysis in terms of hemodynamic changes between vascular geometry and coronary no-reflow.
Aim: We aimed to elucidate the relationship between vascular geometry and coronary no-reflow.
Methods: We reviewed PCI database of our hospital and enrolled a total of 120 patients with STEMI who developed no-reflow following PCI and sex and age matched 80 patients with normal flow. For each group, demographic and clinical characteristics, laboratory values and two dimensional quantitative coronary angiography (QCA) measurements were evaluated.
Results: Patients with no-reflow had a higher prevalence of hypertension and diabetes mellitus. In addition, serum C reactive protein levels were higher in patients with no-reflow compared to patients with normal flow (P

Key words: bifurcation angle; coronary artery; coronary physiology; percutaneous coronary intervention