Aim: Stroke is a sudden onset of focal or global loss of cerebral function and is the most common cause of mortality and morbidity after cancer and heart disease in adulthood. Although it has been reported that mean platelet volume (MPV) values may be an independent risk factor for the severity and prognosis of stroke, the results of the studies are contradictory. The aim of our study was to determine the MPV values reflecting the activity and function of platelets in ischemic stroke patients and to observe its effect on prognosis in ischemic stroke. 62 acute ischemic stroke patients were included in the study.
Materials-Methods: Medical information, MPV values, platelet, white blood cell (WBC) and neutrophil count, CRP and troponin-T values were obtained.
Results: The mean age of the patients was 72.4 ± 12.6 years. At the end of the study, 28 patients were discharged and 34 patients died. The frequency of bilateral stroke was higher in patients who died (p = 0.005). Platelet counts were significantly higher in patients who were discharged than those who died (p = 0.016). MPV values were significantly lower in patients who were discharged (10.59 ± 1.01 fL) than those who died (11.29 ± 1.12 fL) at first admission (p = 0.029). At the end of the study, MPV values were significantly higher in patients who died (11.46 ± 1.28 fL) than those who were discharged (10.47 ± 0.74 fL) (p0.05).
Conclusion: Our study showed that MPV and platelet count may be associated with mortality and can be used as prognostic markers in stroke patients.
Key words: Stroke, Cerebrovascular diseases, MPV, platelet, prognosis
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