Introduction: After severe postpartum bleeding; pituitary hypoperfusion may cause Sheehans syndrome (SS), renal hypoperfusion may cause kidney injury and postpartum infections may trigger hemolysis. Case report: We report a thirty years old patient of hemolytic anemia, Sheehan syndrome and renal failure after postpartum spontaneous uterine artery rupture and infectious process. Discussion: After adequate intensive care, supportive therapies, antibiotherapy and plasmapheresis life- threatening status regressed.
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