Objective: To determine frequency of common bacteria causing urinary tract infection (UTI) among toilet-trained children and their antimicrobial susceptibility pattern.
Methodology: This descriptive cross sectional study was completed from October 2020 to March 2021 at pathology unit of Sahara Medical College, Narowal. It included 193 toilet-trained children with culture positive UTI. Demographic details like gender, age, residential area, and clinical findings along with isolated microorganism and antimicrobial sensitivity pattern were recorded. Mid-stream urinary samples were collected and sent to institutional laboratory for urine analysis, culture and antimicrobial sensitivity patterns.
Results: Out of 193 children, there were 108(54%) female and 91(47.2%) male. Mean age was 10.56±3.82 years (range 6-14). There were 107(55.4%) children above 10 years of age and 122(63.2%) belonged to rural areas. Most common bacteria isolated was E. coli in 155(80.3%) cases. Antimicrobials having highest sensitivity against the causative bacteria include imipenem and meropenem 189(97.9%), piperacillin tazobactam 187(96.9%), amikacin 185(95.8%), fosfomycin 184(95.3%), gentamycin 178(92.2%) and sulzone 171(88.6%).
Conclusion: E. Coli was the commonest bacteria causing UTI among toilet trained children. Antimicrobials with highest sensitivity against the causative organisms include imipenem, meropenem, piperacillin tazobactam, amikacin and fosfomycin.
Key words: Cutaneous infections, Staphylococcus aureus, Streptococcus pyogenes, Antibiotic susceptibility, Bacterial culture and sensitivity.
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