Objective
To observe the relationship between malnutrition and Myocardial Infarction (MI) in
patients with type 2 diabetes.
Methods
This cross sectional comparative study was carried out among the population of Southern
Sindh, Pakistan. The blood samples were collected from MI patients with type 2 diabetes
and 30 samples were collected as control from the same age and gender. Plasma
concentrations of total protein, albumin, globulin and A/G ratio level were used as a
parameter of visceral protein stores. Fat stores were assessed from body fat and total
plasma homocystein level was assessed for the deficiencies of vitamin B12, vitamin B6
and folic acid. Patients having body mass index (BMI) less then 20 kg m-2 were
considered as malnourished
Results
Out of total of 70 patients, 48 were male and 22 were female. Age ranged from 45 to 60
years. BMI in controls was significantly higher (22.9 +/- 4.1 SD) as compared to patients
(18.2 +/- 3.7 SD). Protein and homocystein levels also revealed significantly high values
in controls then patients.
Conclusion
This seems to be a relationship between malnutrition and an increased risk of MI in
patients with type 2 diabetes. (Rawal Med J 2010;35: ).
Key words: Malnutrition, myocardial Infarction, diabetes mellitus.
|