Abstract

Objectives: To investigate sputum inflammatory cell indices and to correlate them with the pulmonary function test in asthmatic adults to assess the severity of asthma.
Methodology: This cross sectional study was carried out from February 2017 to December 2018 in the Department of Physiology, University of Karachi with the collaboration of Department of Chest Medicine, Jinnah Postgraduate Medical Center, Karachi. A total of 140 asthmatic patients of age between 20-60 years of either gender were selected. Patients were diagnosed to be asthmatics according to Global Initiative for Asthma Guideline (GINA). Patient’s biophysical parameters were age, gender and body mass index. Vitalograph compact was used to perform spirometry. Sputum cell profile was performed by Leishman’s stain. The study was analyzed statistically by SPSS version 21 and p

Key words: Asthma, inflammatory cells, pulmonary function test.