The aim of the study was to investigate the incidence and factors linked with nonalcoholic fatty liver disease (NAFLD) among type-2 diabetes mellitus (T2DM) patients in Warangal, Telangana, India. It was an observational, cohort crosssectional study; a target sample of 100 T2DM patients was recruited from a single study site of Warangal. Detailed medical history was obtained and laboratory examinations and ultrasound imaging were carried out to evaluate the NAFLD. The overall incidence of NAFLD was 80%. The risk of NAFLD was significantly high in subjects with uncontrolled blood glucose levels, abnormal waist circumference, increased aspartate aminotransferase (AST), and elevated triglyceride levels (p < 0.05). In our study subjects, the consumption of alcohol is the predominant risk factor (Odds ratio: 6.652; 95% confident interval: 1.86–23.74 and p = 0.00*) significantly causing NAFLD among the study subjects. Grade-1 and 2 fatty livers are typically associated with elevated AST levels and a high incidence was observed in men.
Non-alcoholic fatty liver disease; type-2 diabetes mellitus; South India
Promoter CAG is more efficient than hepatocyteâ€‘targeting TBG for transgene expression via rAAV8 in liver tissues.
Kang J, Hang L, Zheng W, Luo J, Zhang X, Song Y, Liu A
Molecular medicine reports. 2022; 25(1):
Exploring the Alzheimer's disease neuroepigenome: recent advances and future trends.
Zhang H, Elefant F
Neural regeneration research. 2022; 17(2): 325-327
Editorial: Novel therapeutic approaches in chronic kidney disease and kidney transplantation: the draw of evolving integrated multimodal approaches in the targeted therapy era.
Tantisattamo E, Hanna RM, Kalantar-Zadeh K
Current opinion in nephrology and hypertension. 2022; 31(1): 1-5
Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease.
Goulding SR, Anantha J, Collins LM, Sullivan AM, O'Keeffe GW
Neural regeneration research. 2022; 17(1): 38-44
Differentiating Human Pluripotent Stem Cells to Vascular Endothelial Cells for Regenerative Medicine, Tissue Engineering, and Disease Modeling.
Bertucci T, Kakarla S, Kim D, Dai G
Methods in molecular biology (Clifton, N.J.). 2022; 2375(): 1-12