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ECB. 2015; 4(12): 543-547 CATALYSIS BY TRIFLIC ACID: SYNTHESIS OF
THE INDOLYLQUINONES AS POTENTIAL
ANTITUMOR AGENTFeyriel Dridi, Didier Villemin, Nathalie Bar, Messaoud Hachemi, RemiLegay. Abstract | | | | Trifluoromethanesulfonic acid efficiently catalyzes the conjugate addition of indoles to p-benzoquinones under mild conditions affording
the corresponding indolylquinones in high yields with high selectivity. In particular, the poorly reactive menadione underwent reaction with
indoles under similar conditions to give 3-indolylnaphthoquinones.
Key words: p-Quinones, indoles, trifluoromethanesulfonic acid, indol-3-ylbenzoquinones.
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