Objectives
To determine the suitable and ideal doses of remifentanil which provide acceptable tracheal
intubating conditions in children given propofol.
Methods
This prospective double blind trial was performed on 60 ASA 1 and 2 children aged
between 3 and 12 years at Nikokari University Hospital, Tabriz, Iran from June 2007 to
April 2008. The patients were randomly allocated to one of four groups. Patients in groups
1, 2, 3, and 4 received 1, 2, 3μg/kg remifentanil; and 0.5mg/kg atracurium, respectively.
Then, all patients were injected 3 mg/kg of propofol, and underwent tracheal intubation.
The intubating conditions were evaluated and recorded according to the Helbo-Hansen
scoring system.
Results
Tracheal intubation was successful in 58 of 60 patients. Intubation failed only in two patients of
group 1, but was performed after injection of additional drug. The difference of total conditions of
tracheal intubation between groups 1 and 4 was significant (33% vs. 80%); the difference
of total conditions between groups 3 and 4 was not significant (P=0.427); but the difference
of total conditions between 4 groups was significant (P=0.043).
Conclusion
Intubating conditions in children following administration of remifentanil 3 μg/kg were
more suitable who were given propofol. (Rawal Med J 2010;35: ).
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