Original Article |
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ECB. 2015; 4(10): 460-462 A NEW REAGENT FOR THE SYNTHESIS OF
PYRAZOLO[4,3-e][1,2,4]TRIAZOLO[1,5-c]PYRIMIDINESKhidmet S. Shikhaliev, Evgeniya A. Kosheleva, Lyudmila F. Ponomaryeva, Michael Yu. Krysin. Abstract | | | | Tandem reaction of N'-(4-cyano-1-phenyl-1H-pyrazol-5-yl)-N,N-dimethylimidoformamide (6) with acylhydrazines in N,Ndimethylacetamide leads to the formation of 2-R-7-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines (10a-f).
Key words: pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines; aminopyrazole; acylhydrazines; N,N-dimethylformamide dimethylacetal;
tandem reaction.
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