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Original Research

RMJ. 2020; 45(4): 790-793


Biochemical parameters and comparison with CA 15-3 in premenopausal females with BRCA

Maira Mahmood, Arham Javed, Uzma Jabbar, Muhammad Fahim ul Haq, Naim Ahmad Nizami, Farah Bano Niazi.




Abstract

Objective: To find the correlation of CA 15-3 with serum Ferritin and serum LDH in different stages BRCA.
Methodology: A case control study was designed and included 70 patients with different stages of BRCA. Twenty normal subjects with no history of any disease or malignancy were taken as healthy controls. Estimation of serum LDH, serum CA 15-3 and serum ferritin was carried out by standard methods.
Results: The levels of CA 15-3 along with serum ferritin and serum LDH were progressively increased in BRCA women from stage IV to stage 4. A significant correlation was observed between CA 15-3, serum LDH and serum Ferritin in advanced stages of BRCA.
Conclusion: Levels of serum CA 15-3, serum ferritin and serum LDL are associated with tumor extent as their significantly increased values were observed in BRCA. A significant correlation was observed between and advanced stages of BRCA.
Keywords: Tumor markers, LDH, ferritin.

Key words: Tumor markers, LDH, ferritin.






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