Dual natural infection with bovine viral diarrhea virus (BVDV)-1 and BVDV-2 in a stillborn calf: tissue distribution and molecular characterization
Maximiliano Joaquín Spetter, Enrique Leopoldo Louge Uriarte, Erika Analía González Altamiranda, María Rosa Leunda, Susana Beatriz Pereyra, Andrea Elizabeth Verna, Anselmo Carlos Odeón.
Dual infections with both bovine viral diarrhea virus (BVDV)-1 and -2 seem to be unusual. The aim of this study was to describe an infection with both BVDV genotypes in a stillborn calf. Virus isolation and phylogenetic analyses of the 5´UTR and NS5B regions confirmed the presence of BVDV-1b and -2b in spleen and lung, whereas BVDV-2b was also detected in brain, heart, liver, kidney and, fluid of cavities. These results confirm that dual infections with both BVDV-1 and BVDV-2 species can occur naturally and their tissue distribution can be different.
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