Forty-five children who underwent distal hypospadias surgery were assigned to group one (n=23) received caudal bupivacaine (0.25%) 0.5 mg kg-1 and midazolam 0.05 mg kg-1 before the surgical incision, and group two (n=22) who received caudal bupivacaine (0.25%) 0.5 mg kg-1 and midazolam 0.05 mg kg-1, after the surgical incision. Anesthesia was induced with propofol and fentanyl and maintained with sevoflurane and nitrous oxide. Postoperative pain was rated on objective pediatric pain scale. Analgesic requirement was higher in the second group.
Key words: Preemptive analgesia, Caudal block, Midazolam, Postoperative pain.
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