ANTITUMOR AND ANTIOXIDANT ACTIVITY OF ESCHERICHIA
COLI IS ACCOMPANIED BY CHANGES IN THE L-ARGININE
DICHOTOMOUS PATHWAYS IN PERITONEAL AND BLOOD
LEUKOCYTES FOLLOWING EHRLICH ASCITES
CARCINOMA

N. Kh. Alchujyan; H. A. Movsesyan; A. A. Aghababova; A. G. Guevorkyan; N. H. Movsesyan; H. F. Khachatryan; V. H. Barseghyan; H. L. Hairapetyan; L. S. Sahakyan; L. G. Avanesyan; L. H. Melkonyan; K. A. Barseghyan; G. A.Kevorkian

ECB. 2015; 4(7): 317-326

ANTITUMOR AND ANTIOXIDANT ACTIVITY OF ESCHERICHIA COLI IS ACCOMPANIED BY CHANGES IN THE L-ARGININE DICHOTOMOUS PATHWAYS IN PERITONEAL AND BLOOD LEUKOCYTES FOLLOWING EHRLICH ASCITES CARCINOMA

N. Kh. Alchujyan, H. A. Movsesyan, A. A. Aghababova, A. G. Guevorkyan, N. H. Movsesyan, H. F. Khachatryan, V. H. Barseghyan, H. L. Hairapetyan, L. S. Sahakyan, L. G. Avanesyan, L. H. Melkonyan, K. A. Barseghyan, G. A.Kevorkian.

Abstract
The effectiveness and mechanisms of antitumor activity of non-pathogenic Escherichia coli EM0 strain using mouse model of Ehrlich ascites carcinoma (EAC) is studied. 48 h after inoculating EAC cells, a single noninvasive treatment of the 2-month-old male white mice’s eyes and mouths with live E. coli isolate increased the life span by 75% (P Key words: : arginase, cytoplasm, Ehrlich ascites carcinoma, Escherichia coli, leukocyte, lipid peroxidation, mitochondria, nitric oxide synthase.

ANTITUMOR AND ANTIOXIDANT ACTIVITY OF ESCHERICHIA COLI IS ACCOMPANIED BY CHANGES IN THE L-ARGININE DICHOTOMOUS PATHWAYS IN PERITONEAL AND BLOOD LEUKOCYTES FOLLOWING EHRLICH ASCITES CARCINOMA

Abstract