The growth of new blood vessels contributes to numerous malignant, ischemic, inflammatory, infectious and immune disorders. There are
two forms of vascular remodeling associated with physiological and pathological processes; angiogenesis and arteriogenesis. It is shown in
this study that, practically in all investigated models, the process of intussusceptive angiogenesis, etc. is the first step. Chemical agents lead
to the development of intussusceptive angiogenesis in liver that could be the main reason for hemodynamic disturbance.
Key words: TEM, intussusceptive angiogenesis, liver
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