SILICA GEL SUPPORTED -FERRITE AS A HETEROGENOUS
CATALYST FOR HIGH YIELD SYNTHESIS OF β-LACTAMS (2-
AZETIDINONES) UNDER ECO-FRIENDLY CONDITIONS VIA
1,2,4-TRIAZOLES
Kalpana Avasthi, Ritu Yadav, Ashish Bohre.
Abstract
A mild and efficient method has been reported for the preparation of Schiff base through the condensation reaction of various aromatic
aldehydes with substituted aromatic amines in the presence of silica supported γ-Ferrite (ferric oxide) as a heterogeneous catalyst under
solvent-free conditions. and this Schiff base used for Environmentally benign synthesis followed by the reaction with chloroacetylchloride
in green conditions to yield the β-lactams (a-l) with excellent yields. The advantages of this eco-friendly, mild economic method are such as
simplicity of the reaction procedure, moderate to high product yields, and simple working steps, very short reaction times
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