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Case Report



Pancytopenia and hemolysis secondary to pernicious anemia

Diogo Costa Santos, Graça Lérias, Isabel Madruga.




Abstract
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Cobalamin deficiency is a common cause of anaemia frequently presenting with an insidious onset of manifestations. Pancytopenia and hemolysis are rarely described in the literature. We report a case of a 73-year-old woman presenting with fatigue, anorexia and significant weight loss, found to have megaloblastic anaemia in association with pancytopenia and hemolysis. Work-up revealed vitamin B12 deficiency secondary to pernicious anaemia caused by atrophic gastritis.

Key words: Hemolysis, Pancytopenia, Pernicious anemia, Vitamin B12 deficiency





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