Abstract

An efficient and mild synthesis of some diverse iminosaccharides of pyrazole has been carried out. Compounds (8a-b) have been
synthesized by the treatment of isoniazide with chalcones (6a-b) using [bbim][BF4] ionic liquid as a solvent under microwave irradiation.
Compounds (8a-b) on reaction with various aldoses afforded corresponding iminosaccharides compounds containing pyrazole moiety (9al) in presence of ionic liquid under microwaves. The products have been isolated, purified and characterized by different spectral methods
i.e. IR, 1H NMR, 13C NMR and Mass spectra. The potent antimicrobial effects (MIC) of the synthesized compounds were investigated.

Key words: [bbim][BF4], iminosaccharides, ionic liquid, microwave irradiation, green chemistry