Contagious bovine pleuropneumonia is a trans-boundary animal disease caused by Mycoplasma mycoides subsp. mycoides. This study was designed to determine the seroprevalence of contagious bovine pleuropneumonia (CBPP) in three selected south eastern states (Anambra, Enugu and Imo) of Nigeria using competitive enzyme-linked immunosorbent assay (c-ELISA). A total of 438 bovine sera samples were collected randomly for four months (December 2019 to March 2020) and screened for antibodies to Mycoplasma mycoides subsp. mycoides (Mmm) using IDEXX CBPP antibody ELISA kit (CIRAD, France). Results showed an overall prevalence of 59.4% for the three states screened. Antibodies to Mmm were detected in all the three states. Enugu state had the highest prevalence (64.3%) followed by Imo state (63%) and Anambra state (50.7%). Female animals had higher prevalence of CBPP than male. However, it was not statistically significant (P> 0.05). This study confirms the presence of CBPP in south eastern Nigeria, and could be used as a base line data for future studies in this region. It is recommended that active surveillance and vaccination protocol should be undertaken in the region for the control and prevention of this disease.
Key words: c-ELISA, Contagious bovine pleuropneumonia, Mycoplasma , Nigeria, Seroprevalence
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