Abstract

The phenomenon of plasmatic membrane (PM) thickness was seldom noted at investigation of cells in different organs. However just
presence of such a phenomena was noted, but no valuation of its biological importance was given. In a basis of excitable and unexcitable
cells plasmatic membrane thickness changes lays cell submembrane layer thickness alteration. Reversible and irreversible damages of its
structures can be a key of cell dysfunction at pathology.

Key words: Transmission electron microscopy, cardiomyocyte subsarcolemma thickness, hepatocytes subcytolemma thickness, inoculation by CCl4, pulmonary arterial valve stenosis.