The phenomenon of plasmatic membrane (PM) thickness was seldom noted at investigation of cells in different organs. However just
presence of such a phenomena was noted, but no valuation of its biological importance was given. In a basis of excitable and unexcitable
cells plasmatic membrane thickness changes lays cell submembrane layer thickness alteration. Reversible and irreversible damages of its
structures can be a key of cell dysfunction at pathology.
Key words: Transmission electron microscopy, cardiomyocyte subsarcolemma thickness, hepatocytes subcytolemma thickness,
inoculation by CCl4, pulmonary arterial valve stenosis.
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