Abstract

The methanolysis of N-acetoxy-N-n-propyloxy-N’,N’-dimethylurea in the presence of strong acids at room temperatures or in the boiling
methanol yields N,N-dimethoxy-N’,N’-dimethylurea as final product. Primarily the nucleophilic substitution acetoxy group at nitrogen on
methoxy group arises. At second stage the transesterification of N,N-dialkoxyamino group of formed N-methoxy-N-n-propyloxy-N’,N’-
dimethylurea take place.

Key words: nucleophilic substitution at nitrogen; N-acyloxy-N-alkoxyureas; N,N-dialkoxyureas; methanolysis.