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Original Article

ECB. 2014; 3(8): 815-822


NON-EXISTENCE OF SECONDARY COORDINATES OF INTERSECTS

V. I. Krupyanko.




Abstract

The analysis of algebraic forms of corrected equations for the calculation of constants of enzyme inhibition (Ki) and activation (Ka) have
shown that the secondary intersects coordinates (1/ V'; i) may be use for calculation only KIIIi constants of noncompetitive enzyme
inhibition. A few examples of application of corrected coordinates are given in the present research article.

Key words: noncompetitive enzyme inhibition; corrected coordinates for calculation of enzyme inhibition and enzyme activation constants; secondary coordinates of intersects






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