We present the potential role of aptamers in elucidating the function of hypothetical proteins, as well as the possibilities provided by
bioinformatics for establishing a benchmark for aptamer-protein prediction methods. With these future perspectives, the role of hypothetical
proteins as target molecules for diagnostics and therapies could prove to be very useful in development of medical technology.
Key words: Aptamers, hypothetical proteins, pull down assay, in silico studies.
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