Wound contraction effect of Bermuda grass (Cynodon dactylon) topical cream on induced second-degree burn in male albino mice
Judee Kriselle Solatan Rallos, Shanine Mae Sebial Caballero, Diana Jane Lao Codilla, Racealle Ag Ni o Pasa Mendez, Alyssa Sasam Obediente, Rhiel Soon Samson, Bea Giles Capisi o Sevillano, Rhea Danica Lamanilao Valle, Jude Nazar Lu Villaranda, Brian Mortejo Denney.
Abstract
The study aimed to determine the effectiveness of Bermuda grass (Cynodon dactylon) topical cream on induced second-degree burns in male albino mice by utilizing a randomized controlled trial experimental research design. The research subjects were assigned randomly into three (3) groups and each containing six (6) mice. Silver sulfadiazine was applied on Group 1 while Base cream was applied on Group 2, and five percent (5%) Bermuda grass topical cream was applied on the Group 3. All treatments were applied every twenty-four (24) hours thereafter while measurement of wound contraction began twenty-four (24) hours after the induction of the burn and every forty-eight (48) hours thereafter until the seventeenth day where complete wound contraction was observed. The study supported the potential of Bermuda grass as a possible alternative for Silver sulfadiazine in the treatment of burn injuries. This was demonstrated by a higher mean (%) wound contraction 93.14±4.59, effect of five percent (5%) Bermuda grass topical cream against the mean percent (%) wound contraction effect of Silver sulfadiazine and Base cream 78.77±8.98 and 89.38±4.24 respectively.
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