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Elevated platelet distribution width in peripheral artery disease

Ayse Sahin Tutak, Huseyin Avni Findikli, Abdulhamit Murat Ercisli, Murat Arcagok.




Abstract
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Aim: This study was planned with the hypothesis that atherosclerosis is in the etiology of peripheral artery disease (PAD), whether symptomatic or not, and therefore thrombocyte-related parameters could show variability.
Material and Methods: A retrospective examination was made of the laboratory records of 48 patients who presented at the Cardiovascular Surgery Polyclinic with mild or severe symptoms and were diagnosed with PAD and a control group of 33 healthy individuals.
Results: No difference was determined between the patient and control groups in respect of age, gender, Platelet Count (Plt), C-reactive protein (CRP), neutrophil-lymphocyte ratio (NLR), Mean Platelet Volume ( MPV), Hemoglobin (Hgb) and White Blood Cells (WBC ) values. The Platelet distribution width (PDW) value of the patient group was found to be statistically significantly higher than that of the control group (p

Key words: Peripheral artery disease; platelet distribution width; atherosclerosis





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