This case report documents the clinical and pathological findings of a dog where metastasis to a rarely documented distant bone site secondary to transitional cell carcinoma was diagnosed before the primary tumor. An 8-year-old female spayed beagle presented with unilateral front-limb lameness in which pain was localized to the shoulder joint. Surgical bone biopsy following abnormal radiographic lesions noted in the scapula was consistent with metastatic carcinoma of unknown origin, but the primary site was speculated to be from mammary gland, urinary bladder, or prostate tissue. Abdominal ultrasound revealed a mass in the trigone region of the urinary bladder, which was cytologically confirmed to be a transitional cell carcinoma.
Key words: transitional cell carcinoma, bone metastasis
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