Pantoprazole is one of the most widely used proton-pump inhibitors for gastric acid suppression. Its better adverse effect profile has resulted in its overprescription and large over-the-counter use. Anaphylactic reaction to pantoprazole is relatively rare. We present a case report of a 38-year-old male who presented with anaphylactic reaction to pantoprazole ranging from a mild rash to potentially life-threatening anaphylactic shock on three different occasions. This case report highlights the importance of proper patient education, their awareness regarding adverse drug reactions to drugs, their role in informing the treating doctors regarding the same, and the need for careful history taking by doctors regarding drug allergies and cautious use of even the most commonly used drugs and those with low incidence of adverse effects.
Key words: Anaphylactic Reactions; Pantoprazole; Proton-pump Inhibitor; Adverse Drug Reaction
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