In the present study, a series of 4-hydroxy-N'-[(1E)-substituted-phenylmethylidene]benzohydrazide analogues was synthesized, characterized and evaluated for their antibacterial and anti-oxidant activity. All the tested compounds show high antibacterial activity with compound AR7, N-(3,4,5-trimethoxybenzylidene)-4-hydroxybenzohydrazide) as the most active compound whereas compound AR10 (hydrogen peroxide scavenging) and AR8 (DPPH scavenging activity method) were found to possess maximum anti-oxidant activity indicating that different mechanisms are involved in different anti-oxidant determination methods.
Key words: Synthesis, Hydrazones, Antibacterial, Antioxidant
|
