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Original Article

J Med Allied Sci. 2023; 13(1): 18-25


Study of clinical presentation, laboratory profile, transfusion requirements and transfusion-related infectious complications in adult patients of congenital hemolytic anemia in a tertiary care center

Sarang Prabhakar Kotrange, Dhirendra Shivprasad Yadav, Niteen Dattatray Karnik, Namita Jitendra Padwal.




Abstract

Congenital hemolytic anemia (CHA) especially hemoglobinopathies is quite prevalent in certain ethnic groups in India and commonly seen in pediatric age group. Adult presentations are being seen due to better treatment options and increased life span. This study was conducted to determine the clinical profile, laboratory parameters, transfusion requirements, and transfusion-related infectious complications of adult patients with CHA. A total of 84 patients of CHA aged more than 12 years were enrolled and studied over 18 months period. 63% patients were males with mean age of 19.98±4.99 SD years and maximum (57%) in the age group of 13-20 years. Family history of CHA was present in 19 (22.61%) patients and consanguinity in 16 (19.04%) cases which were statistically significant (P

Key words: Beta-thalassemia, Congenital hemolytic anemia, Hemoglobin E disease






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