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Research Article

ECB. 2019; 8(11): 363-367


ONE-POT SYNTHESIS OF PHTHALAZIN-4-HETEROYL-4HPYRAN DERIVATIVES IN [BMIM][OH]

D. P. Loka Maheshwari, B. Satyanarayana.



Abstract
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A [bmim][OH] mediated, green and efficient synthesis of phthalazines derivatives have been developed by condensing phthalic acid (1), ethyl cyanohydrazide (2), heteroaromatic aldehydes (3a-3f) and active methylene compounds (4) at 60-65 oC for 60-90 min. The importance of this method includes shorter reaction time and high yield.

Key words: Phthalic acid, ethyl cyanohydrazide, active methylene compounds, heteroaromatic aldehydes, [bmim][OH].





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020304050607080910111201
20252026

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