Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Review Article

J App Pharm Sci. 2021; 11(8): 172-182


Preventive potential of Andrographis paniculata-derived compounds in metabolic syndrome-associated prostate cancer: A narrative review on the mechanism of action

Mohamad Khairul Hafiz Idris, Rosnani Hasham.

Abstract
Metabolic syndrome (MetS) and prostate cancer (PCa) are among the diseases with a concerning prevalence. The reported cases for both medical dilemmas have been steady with no sign of abating at the moment. More worrying is that researchers have started to discover that some of the components of MetS associatively worsen the prognosis of PCa. Even though the relationship is not fully known, its manifestation could cause extra burden to the currently implemented treatment approaches. The use of plant bioactive compounds as an alternative treatment has gained recognition, provided that its mechanisms of action, tolerability, efficacy, safety, and cost-effectiveness are well understood. Therefore, the current review intended to highlight the potential of bioactive compounds derived from plants to simultaneously target MetS, PCa, and MetS–PCa codisease. Additionally, emphasis on the potential of Andrographis paniculata (AP) as a candidate for the treatment of MetS–PCa is also highlighted.

Key words: prostate cancer, metabolic syndrome, Andrographis paniculata, adiposity, hyperglycemia



Similar Articles

Chemometric analysis of the global pattern of volatile organic compounds in the exhaled breath of patients with COVID-19, post-COVID and healthy subjects. Proof of concept for post-COVID assessment.
Zamora-Mendoza BN, DĂ­az de LeĂłn-MartĂ­nez L, RodrĂ­guez-Aguilar M, Mizaikoff B, Flores-RamĂ­rez R
Talanta. 2022; 236(): 122832

A sensitive electrochemiluminescence biosensor for assay of cancer biomarker (MMP-2) based on NGQDs-Ru@SiO2 luminophore.
Fan X, Wang S, Liu H, Li Z, Sun Q, Wang Y, Fan X
Talanta. 2022; 236(): 122830

Hyperglycemia in acute ischemic stroke: physiopathological and therapeutic complexity.
Ferrari F, Moretti A, Villa RF
Neural regeneration research. 2022; 17(2): 292-299

Hypoxia and Proton microbeam: Role of Gap Junction Intercellular Communication in Inducing Bystander Responses on Human Lung Cancer Cells and Normal Cells.
Autsavapromporn N, Kobayashi A, Liu C, Jaikang C, Ahmad TAT, Oikawa M, Konishi T
Radiation research. 2022; ():

Lectin Affinity Chromatography for the Discovery of Novel Cancer Glycobiomarkers: A Case Study with PSA Glycoforms and Prostate Cancer.
Llop E, Peracaula R
Methods in molecular biology (Clifton, N.J.). 2022; 2370(): 301-313


Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.



ScopeMed Web Sites